Basic Information
Symbol
circRAPGEF6
RNA Class
circRNA
Alias
Rap Guanine Nucleotide Exchange Factor 6
RA-GEF-2
PDZ-GEF2
PDZGEF2
PDZ Domain Containing Guanine Nucleotide Exchange Factor (GEF) 2
PDZ Domain-Containing Guanine Nucleotide Exchange Factor 2
Rap Guanine Nucleotide Exchange Factor (GEF) 6
PDZ Domain-Containing Guanine Nucleotide Exchange Factor I
KIA001LB
RAGEF2
Location (GRCh37)
5:130759766-130970853
UCSC Genome Browser
Location (GRCh38)
5:131424073-131635160
Host gene
RAPGEF6
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_RAPGEF6_0021200 | Intron-Intron | chr5:130873438-130873592 | chr5:131537745-131537899 | 155 nt | 0.4645 |
| hsa_RAPGEF6_0022000 | Intron-Exon-Intron | chr5:130883740-130884750 | chr5:131548047-131549057 | 144 nt | 0.3750 |
| hsa_RAPGEF6_0022100 | Intron-Exon-Intron | chr5:130883740-130890508 | chr5:131548047-131554815 | 144 nt | 0.3750 |
| hsa_RAPGEF6_0021700 | Intron-Exon-Intron | chr5:130883740-130899559 | chr5:131548047-131563866 | 2033 nt | 0.3227 |
| hsa_RAPGEF6_0021800 | Intron-Exon-Intron | chr5:130883740-130904466 | chr5:131548047-131568773 | 250 nt | 0.3320 |
| hsa_RAPGEF6_0021900 | Intron-Exon-Intron | chr5:130883740-130955866 | chr5:131548047-131620173 | 250 nt | 0.3080 |
| hsa_RAPGEF6_0022200 | Intron-Exon-Intron | chr5:130883740-130958657 | chr5:131548047-131622964 | 172 nt | 0.3721 |
| hsa_RAPGEF6_0022300 | Intron-Exon-Intron | chr5:130883740-130960027 | chr5:131548047-131624334 | 435 nt | 0.3471 |
| hsa_RAPGEF6_0022400 | Intron-Intron | chr5:130886408-130886561 | chr5:131550715-131550868 | 154 nt | 0.4351 |
| hsa_RAPGEF6_0022500 | Intron-Intron | chr5:130886435-130886629 | chr5:131550742-131550936 | 195 nt | 0.4256 |
Showing 221 to 230 of 253 entries
Forensic Context
A study in mice demonstrated that the circRAPGEF6 was differentially expressed in methamphetamine-treated primary cortical neurons, with RNA sequencing indicating up-regulation, though qRT-PCR validation showed an opposite expression pattern [Li et al. DOI:10.1016/J.Neulet.2019.02.032].