Basic Information

Symbol
circSLC22A6
RNA Class
circRNA
Alias
Solute Carrier Family 22 Member 6 PAHT OAT1 ROAT1 Solute Carrier Family 22 (Organic Anion Transporter), Member 6 Renal Organic Anion Transporter 1 Organic Anion Transporter 1 PAH Transporter HROAT1 HOAT1 HPAHT Para-Aminohippurate Transporter
Location (GRCh37)
11:62697024-62751950 UCSC Genome Browser
Location (GRCh38)
11:62929552-62984478
UCSC Genome Browser Search in Marker Scope
Host gene
SLC22A6
Host category
mRNA
Forensic tag(s)
Tissue/body fluid identification Drug abuse diagnoses
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_chr11_0429600 Intergenic-Intergenic chr11:62697024-62733017 chr11:62929552-62965545 250 nt 0.3640
hsa_chr11_0430000 Intergenic-Intergenic chr11:62718557-62724800 chr11:62951085-62957328 250 nt 0.4320
hsa_chr11_0430100 Intergenic-Intergenic chr11:62720245-62723859 chr11:62952773-62956387 250 nt 0.4120
hsa_chr11_0430200 Intergenic-Intergenic chr11:62723769-62733017 chr11:62956297-62965545 271 nt 0.5203
hsa_chr11_0430300 Intergenic-Intergenic chr11:62729799-62730946 chr11:62962327-62963474 1148 nt 0.4451
hsa_chr11_0430500 Intergenic-Intergenic chr11:62730386-62733017 chr11:62962914-62965545 180 nt 0.5111
hsa_chr11_0430600 Intergenic-Intergenic chr11:62730390-62733017 chr11:62962918-62965545 180 nt 0.5111
hsa_chr11_0430800 Intergenic-Intergenic chr11:62731818-62733017 chr11:62964346-62965545 310 nt 0.4935
hsa_chr11_0430900 Intergenic-Intergenic chr11:62731818-62742460 chr11:62964346-62974988 153 nt 0.5621
hsa_chr11_0431200 Intergenic-Intergenic chr11:62732838-62733017 chr11:62965366-62965545 180 nt 0.5111
Showing 1 to 10 of 13 entries
Forensic Context

A study in mice demonstrated that cocaine self-administration induces differential expression of 90 striatal circular RNAs, with 18 up-regulated and 72 down-regulated [Bu et al. DOI:10.1038/S41398-019-0527-1]. A study in humans demonstrated that circular transcripts of SLC22A6 are specifically expressed in urine and serve as a urine-specific biomarker for body fluid identification, with its inclusion in detection assays not impairing specificity [Liu et al. DOI:10.1007/s00414-019-02027-y]. circSLC22A6 harbors a low expression level of circular transcripts but maintains a high level of expression with a tissue-specific pattern, validating its forensic application for distinguishing urine from other forensically relevant body fluids [Song et al. DOI:10.1007/s00414-023-03091-1].