Basic Information
Symbol
circSNCA
RNA Class
circRNA
Alias
Synuclein Alpha
NACP
Alpha-Synuclein
PARK1
PD1
Synuclein, Alpha (Non A4 Component Of Amyloid Precursor)
PARK4
Parkinson Disease (Autosomal Dominant, Lewy Body) 4
Non A4 Component Of Amyloid Precursor
Non-A4 Component Of Amyloid Precursor
Non A-Beta Component Of AD Amyloid
Non-A Beta Component Of AD Amyloid
Synuclein Alpha-140
I+/--Synuclein
Α-Synuclein
Location (GRCh37)
4:90645338-90758129
UCSC Genome Browser
Location (GRCh38)
4:89724187-89836978
Host gene
SNCA
Host category
mRNA
Forensic tag(s)
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_SNCA_0000400 | Exon-Exon | chr4:90647637-90647750 | chr4:89726486-89726599 | 114 nt | 0.4211 |
| hsa_SNCA_0002300 | Exon-Exon | chr4:90743397-90743539 | chr4:89822246-89822388 | 143 nt | 0.5455 |
| hsa_RP11-115D19.1_0001000 | Intron-Intron | chr4:90645713-90646708 | chr4:89724562-89725557 | 996 nt | 0.3283 |
| hsa_RP11-115D19.1_0001100 | Intron-Intron | chr4:90645859-90646163 | chr4:89724708-89725012 | 305 nt | 0.3443 |
| hsa_RP11-115D19.1_0001200 | Intron-Intron | chr4:90646428-90646607 | chr4:89725277-89725456 | 180 nt | 0.3389 |
| hsa_RP11-115D19.1_0001300 | Intron-Intron | chr4:90646428-90646995 | chr4:89725277-89725844 | 568 nt | 0.3327 |
| hsa_RP11-115D19.1_0001400 | Intron-Intron | chr4:90647313-90647506 | chr4:89726162-89726355 | 194 nt | 0.2680 |
| hsa_RP11-115D19.1_0001500 | Intron-Intergenic | chr4:90647507-90647690 | chr4:89726356-89726539 | 184 nt | 0.4076 |
| hsa_RP11-115D19.1_0001600 | Exon-Intergenic | chr4:90647627-90648819 | chr4:89726476-89727668 | 1193 nt | 0.3512 |
| hsa_SNCA_0000200 | Exon-Exon | chr4:90645338-90645849 | chr4:89724187-89724698 | 512 nt | 0.3574 |
Showing 1 to 10 of 38 entries
Forensic Context
A study in human SH-SY5Y cells demonstrated that the circSNCA functions as a sponge for miR-7, thereby up-regulating SNCA mRNA expression, which results in reduced autophagy and increased apoptosis [Di Agostino et al. DOI:10.3389/fcell.2020.00389].