Basic Information

Symbol
circSNCA
RNA Class
circRNA
Alias
Synuclein Alpha NACP Alpha-Synuclein PARK1 PD1 Synuclein, Alpha (Non A4 Component Of Amyloid Precursor) PARK4 Parkinson Disease (Autosomal Dominant, Lewy Body) 4 Non A4 Component Of Amyloid Precursor Non-A4 Component Of Amyloid Precursor Non A-Beta Component Of AD Amyloid Non-A Beta Component Of AD Amyloid Synuclein Alpha-140 I+/--Synuclein Α-Synuclein
Location (GRCh37)
4:90645338-90758129 UCSC Genome Browser
Location (GRCh38)
4:89724187-89836978
UCSC Genome Browser Search in Marker Scope
Host gene
SNCA
Host category
mRNA
Forensic tag(s)
Forensic psychiatry evaluation
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_chr4_0635300 Intergenic-Intergenic chr4:90676867-90677278 chr4:89755716-89756127 412 nt 0.4490
hsa_SNCA_0001400 Intron-Exon-Intron chr4:90680009-90756843 chr4:89758858-89835692 368 nt 0.5163
hsa_SNCA_0001500 Intron-Exon-Intron chr4:90681751-90756843 chr4:89760600-89835692 188 nt 0.4840
hsa_SNCA_0001600 Intron-Intron chr4:90712205-90712813 chr4:89791054-89791662 609 nt 0.3908
hsa_SNCA_0001700 Intron-Intron chr4:90712205-90712816 chr4:89791054-89791665 612 nt 0.3905
hsa_SNCA_0001800 Intron-Exon-Intron chr4:90712205-90756843 chr4:89791054-89835692 42 nt 0.5714
hsa_SNCA_0001900 Intron-Exon-Intron chr4:90712643-90756843 chr4:89791492-89835692 250 nt 0.3160
hsa_SNCA_0002000 Intron-Exon-Intron chr4:90712707-90756843 chr4:89791556-89835692 256 nt 0.4258
hsa_chr4_0635400 Intergenic-Intergenic chr4:90715910-90716081 chr4:89794759-89794930 172 nt 0.3081
hsa_SNCA_0002100 Intron-Intron chr4:90717937-90718208 chr4:89796786-89797057 272 nt 0.2978
Showing 21 to 30 of 38 entries
Forensic Context

A study in human SH-SY5Y cells demonstrated that the circSNCA functions as a sponge for miR-7, thereby up-regulating SNCA mRNA expression, which results in reduced autophagy and increased apoptosis [Di Agostino et al. DOI:10.3389/fcell.2020.00389].