Basic Information

Symbol
circTMEM165
RNA Class
circRNA
Alias
Transmembrane Protein 165 TPARL SLC64A1 TMPT27 GDT1 Putative Divalent Cation/Proton Antiporter TMEM165 Transmembrane Protein TPARL Transmembrane Protein PT27 TPA Regulated Locus CDG2K FT27
Location (GRCh37)
4:56225513-56310050 UCSC Genome Browser
Location (GRCh38)
4:55359346-55443883
UCSC Genome Browser Search in Marker Scope
Host gene
TMEM165
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_TMEM165_0004700 Intron-Exon-Intron chr4:56283970-56292342 chr4:55417803-55426175 1089 nt 0.3444
hsa_TMEM165_0005000 Exon-Exon chr4:56290705-56290810 chr4:55424538-55424643 106 nt 0.5283
hsa_AC069200.1_0000100 Intergenic-Exon-Intergenic chr4:56262215-56277799 chr4:55396048-55411632 471 nt 0.6518
hsa_CLOCK_0001200 Intron-Intron chr4:56307103-56307330 chr4:55440936-55441163 228 nt 0.3904
hsa_SRD5A3_0000500 Exon-Intergenic chr4:56225513-56262563 chr4:55359346-55396396 250 nt 0.4680
hsa_TMEM165_0000300 Intron-Intron chr4:56263286-56265420 chr4:55397119-55399253 153 nt 0.5425
hsa_TMEM165_0000200 Intron-Exon-Intron chr4:56263286-56269505 chr4:55397119-55403338 250 nt 0.3880
hsa_TMEM165_0000400 Intron-Intron chr4:56264534-56265711 chr4:55398367-55399544 1178 nt 0.3769
hsa_TMEM165_0000500 Intron-Exon-Intron chr4:56265253-56269505 chr4:55399086-55403338 174 nt 0.3851
hsa_TMEM165_0000600 Intron-Exon-Intron chr4:56265253-56275239 chr4:55399086-55409072 168 nt 0.3810
Showing 11 to 20 of 57 entries
Forensic Context

A study in humans demonstrated that the circTMEM165 (hsa_circ_0001414) was significantly upregulated in the peripheral blood of myocardial infarction patients compared to healthy controls, as identified by RNA sequencing and validated by RT-qPCR [Li et al. DOI:10.3389/fcvm.2022.810257]. A study in human patients with ST-segment elevation myocardial infarction (STEMI) identified the circTMEM165 as a differentially expressed circular RNA in peripheral blood, a finding that was confirmed in an AC16 cell model [Wang et al. DOI:10.1515/med-2023-0807].