Forensic RNA Knowledge Base

Basic Information

Symbol

circVPS13C

RNA Class

circRNA

Alias

Vacuolar Protein Sorting 13 Homolog C KIAA1421 BLTP5C PARK23 Bridge-Like Lipid Transfer Protein Family Member 5C Vacuolar Protein Sorting-Associated Protein 13C Intermembrane Lipid Transfer Protein VPS13C FLJ20136 FLJ10381 Vacuolar Protein Sorting 13 Homolog C (S. Cerevisiae) Vacuolar Protein Sorting 13C (Yeast)

Location (GRCh37)

15:62299507-62306191 UCSC Genome Browser

Location (GRCh38)

15:62007308-62013992

UCSC Genome Browser Search in Marker Scope

Host gene

VPS13C

Host category

mRNA

Forensic tag(s)

Drug abuse diagnoses

External database

circbank

Transcripts

ID	Type	Location (GRCh37)	Location (GRCh38)	Length	GC content
hsa_VPS13C_0034900	Exon-Exon	chr15:62299507-62306191	chr15:62007308-62013992	606 nt	0.3630

Forensic Context

A study in mice demonstrated that cocaine self-administration induces differential expression of 90 striatal circular RNAs, with 18 up-regulated and 72 down-regulated [Bu et al. DOI:10.1038/S41398-019-0527-1]. The literature indicates that circular RNAs, including the circVPS13C, can function as miRNA sponges and their specific expression patterns are associated with disease states, supporting their potential as biomarkers [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in humans identified the circVPS13C as potentially playing a crucial role in the pathogenesis and progression of acute ischemic stroke by regulating the miR-337-3p/Bcl2 axis [Wei et al. DOI:10.1186/s12883-021-02397-0].