Basic Information
Symbol
circVPS35
RNA Class
circRNA
Alias
VPS35 Retromer Complex Component
MEM3
PARK17
Vacuolar Protein Sorting-Associated Protein 35
Maternal-Embryonic 3
FLJ10752
HVPS35
Vacuolar Protein Sorting 35 Homolog (S. Cerevisiae)
Vacuolar Protein Sorting 35 Homolog
VPS35, Retromer Complex Component
Vesicle Protein Sorting 35
Location (GRCh37)
16:46708226-46711310
UCSC Genome Browser
Location (GRCh38)
16:46674314-46677398
Host gene
VPS35
Host category
mRNA
Forensic tag(s)
Sudden death from CNS diseases
Sudden cardiac death diagnosis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_VPS35_0004200 | Exon-Exon | chr16:46708226-46711310 | chr16:46674314-46677398 | 440 nt | 0.3841 |
Forensic Context
A study in humans identified the circVPS35 as a potential biomarker for immune-mediated demyelinating disease, where its levels in cerebrospinal fluid exosomes were specifically characterized [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery segments from a single autopsy case identified hsa_circ_0002500 as a co-overexpressed circRNA in both LAD and RCA samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].