Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0004100 Exon-Exon chr2:61710092-61717911 chr2:61482957-61490776 925 nt 0.3784
hsa_XPO1_0000100 Exon-Exon chr2:61705069-61708416 chr2:61477934-61481281 1130 nt 0.3425
hsa_XPO1_0000200 Exon-Exon chr2:61705069-61713097 chr2:61477934-61485962 1789 nt 0.3522
hsa_XPO1_0000300 Exon-Exon chr2:61705069-61720188 chr2:61477934-61493053 2857 nt 0.3591
hsa_XPO1_0000900 Intron-Intron chr2:61706510-61706810 chr2:61479375-61479675 301 nt 0.4286
hsa_XPO1_0001400 Exon-Exon chr2:61708320-61711240 chr2:61481185-61484105 561 nt 0.3619
hsa_XPO1_0001500 Exon-Exon chr2:61708320-61713097 chr2:61481185-61485962 756 nt 0.3664
hsa_XPO1_0001600 Exon-Exon chr2:61708320-61717911 chr2:61481185-61490776 1182 nt 0.3723
hsa_XPO1_0001700 Exon-Exon chr2:61708320-61722748 chr2:61481185-61495613 2181 nt 0.3682
hsa_XPO1_0001800 Exon-Exon chr2:61708320-61761038 chr2:61481185-61533903 250 nt 0.2960
Showing 1 to 10 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].