Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0021400 Exon-Exon chr2:61729131-61729445 chr2:61501996-61502310 107 nt 0.3458
hsa_XPO1_0021500 Exon-Exon chr2:61729131-61761038 chr2:61501996-61533903 414 nt 0.3768
hsa_XPO1_0021800 Exon-Exon chr2:61729384-61753656 chr2:61502249-61526521 237 nt 0.3755
hsa_XPO1_0021900 Exon-Exon chr2:61729384-61761038 chr2:61502249-61533903 369 nt 0.3875
hsa_XPO1_0023300 Intron-Exon-Intron chr2:61743477-61749818 chr2:61516342-61522683 250 nt 0.2640
hsa_XPO1_0023400 Intron-Exon-Intron chr2:61743477-61753656 chr2:61516342-61526521 250 nt 0.2880
hsa_XPO1_0024400 Exon-Exon chr2:61749746-61749818 chr2:61522611-61522683 73 nt 0.3699
hsa_XPO1_0024500 Intron-Exon-Intron chr2:61749746-61752468 chr2:61522611-61525333 2723 nt 0.3511
hsa_XPO1_0024600 Exon-Exon chr2:61749746-61753656 chr2:61522611-61526521 175 nt 0.3714
hsa_XPO1_0024700 Exon-Exon chr2:61749746-61761038 chr2:61522611-61533903 307 nt 0.3876
Showing 91 to 100 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].