Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0025900 Exon-Exon chr2:61749746-61764803 chr2:61522611-61537668 1266 nt 0.5616
hsa_XPO1_0024800 Exon-Exon chr2:61749746-61765418 chr2:61522611-61538283 1029 nt 0.5394
hsa_XPO1_0026400 Intron-Exon-Intron chr2:61752627-61753656 chr2:61525492-61526521 1030 nt 0.3136
hsa_XPO1_0026600 Exon-Exon chr2:61753555-61761038 chr2:61526420-61533903 234 nt 0.3932
hsa_XPO1_0026900 Exon-Exon chr2:61760907-61761038 chr2:61533772-61533903 132 nt 0.4091
hsa_RP11-355B11.2_0000200 Intron-Intergenic chr2:61709552-61719780 chr2:61482417-61492645 123 nt 0.3089
hsa_RP11-355B11.2_0000300 Intron-Intergenic chr2:61710122-61715393 chr2:61482987-61488258 199 nt 0.3518
hsa_USP34_0075300 Exon-Intergenic chr2:61605498-61713097 chr2:61378363-61485962 250 nt 0.3280
hsa_USP34_0076500 Exon-Intergenic chr2:61621988-61761038 chr2:61394853-61533903 250 nt 0.3000
hsa_XPO1_0000700 Exon-Exon chr2:61705898-61709674 chr2:61478763-61482539 461 nt 0.3688
Showing 101 to 110 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].