Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0005700 Exon-Exon chr2:61710092-61713097 chr2:61482957-61485962 304 nt 0.3717
hsa_XPO1_0005200 Exon-Exon chr2:61710092-61715406 chr2:61482957-61488271 606 nt 0.3762
hsa_XPO1_0005300 Exon-Exon chr2:61710092-61717862 chr2:61482957-61490727 876 nt 0.3756
hsa_XPO1_0005400 Intron-Exon-Intron chr2:61710092-61720193 chr2:61482957-61493058 1572 nt 0.3715
hsa_XPO1_0005500 Exon-Exon chr2:61710092-61722748 chr2:61482957-61495613 1924 nt 0.3706
hsa_XPO1_0004900 Exon-Exon chr2:61710092-61725927 chr2:61482957-61498792 2173 nt 0.3709
hsa_XPO1_0005000 Intron-Exon-Intron chr2:61710092-61741318 chr2:61482957-61514183 250 nt 0.3840
hsa_XPO1_0005100 Exon-Exon chr2:61710092-61749818 chr2:61482957-61522683 2584 nt 0.3688
hsa_XPO1_0006100 Exon-Exon chr2:61711072-61713097 chr2:61483937-61485962 364 nt 0.3819
hsa_XPO1_0006200 Exon-Exon chr2:61711072-61719883 chr2:61483937-61492748 182 nt 0.3571
Showing 131 to 140 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].