Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0006300 Exon-Exon chr2:61711072-61720188 chr2:61483937-61493053 139 nt 0.3597
hsa_XPO1_0006000 Exon-Exon chr2:61711072-61729445 chr2:61483937-61502310 2376 nt 0.3695
hsa_XPO1_0006400 Intron-Exon-Intron chr2:61712045-61745427 chr2:61484910-61518292 250 nt 0.4040
hsa_XPO1_0006500 Intron-Exon-Intron chr2:61712111-61718096 chr2:61484976-61490961 320 nt 0.4094
hsa_XPO1_0007700 Exon-Exon chr2:61712903-61719606 chr2:61485768-61492471 932 nt 0.3777
hsa_XPO1_0007800 Exon-Exon chr2:61712903-61719883 chr2:61485768-61492748 1124 nt 0.3737
hsa_chr2_0891300 Intergenic-Intergenic chr2:61712953-61717850 chr2:61485818-61490715 74 nt 0.3784
hsa_XPO1_0007900 Intron-Intron chr2:61714479-61714784 chr2:61487344-61487649 306 nt 0.2843
hsa_XPO1_0009000 Exon-Exon chr2:61715300-61715906 chr2:61488165-61488771 107 nt 0.3832
hsa_XPO1_0008800 Exon-Exon chr2:61715300-61719616 chr2:61488165-61492481 747 nt 0.3762
Showing 141 to 150 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].