Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0009100 Exon-Exon chr2:61715300-61719883 chr2:61488165-61492748 107 nt 0.3832
hsa_XPO1_0008900 Exon-Exon chr2:61715300-61724142 chr2:61488165-61497007 1554 nt 0.3707
hsa_XPO1_0009200 Exon-Exon chr2:61715300-61726048 chr2:61488165-61498913 107 nt 0.3832
hsa_XPO1_0008600 Intron-Exon-Intron chr2:61715300-61743847 chr2:61488165-61516712 250 nt 0.4040
hsa_XPO1_0008700 Intron-Exon-Intron chr2:61715300-61761813 chr2:61488165-61534678 250 nt 0.3720
hsa_XPO1_0009300 Intron-Exon chr2:61715719-61715859 chr2:61488584-61488724 141 nt 0.3688
hsa_XPO1_0009400 Exon-Exon chr2:61715723-61717911 chr2:61488588-61490776 319 nt 0.3824
hsa_XPO1_0009500 Exon-Exon chr2:61715723-61719616 chr2:61488588-61492481 640 nt 0.3750
hsa_XPO1_0010600 Exon-Exon chr2:61717777-61721226 chr2:61490642-61494091 975 nt 0.3723
hsa_XPO1_0010700 Exon-Exon chr2:61717777-61725927 chr2:61490642-61498792 135 nt 0.3926
Showing 151 to 160 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].