Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0010800 Exon-Exon chr2:61717777-61749818 chr2:61490642-61522683 208 nt 0.3846
hsa_XPO1_0010900 Intron-Intron chr2:61717912-61719169 chr2:61490777-61492034 1258 nt 0.4674
hsa_XPO1_0011700 Exon-Exon chr2:61719170-61719616 chr2:61492035-61492481 321 nt 0.3676
hsa_XPO1_0012100 Exon-Exon chr2:61719170-61719883 chr2:61492035-61492748 164 nt 0.3902
hsa_XPO1_0012200 Exon-Exon chr2:61719170-61720188 chr2:61492035-61493053 460 nt 0.3652
hsa_XPO1_0011800 Exon-Exon chr2:61719170-61721244 chr2:61492035-61494109 858 nt 0.3695
hsa_XPO1_0011900 Exon-Exon chr2:61719170-61726048 chr2:61492035-61498913 1297 nt 0.3647
hsa_XPO1_0012000 Exon-Exon chr2:61719170-61749818 chr2:61492035-61522683 1659 nt 0.3635
hsa_XPO1_0012300 Exon-Exon chr2:61719170-61753656 chr2:61492035-61526521 108 nt 0.3796
hsa_XPO1_0012400 Exon-Exon chr2:61719170-61764722 chr2:61492035-61537587 190 nt 0.4053
Showing 161 to 170 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].