Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0012500 Exon-Exon chr2:61719248-61726889 chr2:61492113-61499754 1261 nt 0.3664
hsa_chr2_0891400 Intergenic-Intergenic chr2:61719307-61719529 chr2:61492172-61492394 97 nt 0.4330
hsa_XPO1_0012600 Exon-Exon chr2:61719460-61719616 chr2:61492325-61492481 157 nt 0.3439
hsa_XPO1_0012700 Exon-Exon chr2:61719460-61721226 chr2:61492325-61494091 676 nt 0.3639
hsa_XPO1_0012800 Exon-Exon chr2:61719460-61722748 chr2:61492325-61495613 835 nt 0.3581
hsa_XPO1_0012900 Exon-Exon chr2:61719460-61724142 chr2:61492325-61497007 964 nt 0.3620
hsa_XPO1_0013000 Exon-Exon chr2:61719460-61725927 chr2:61492325-61498792 210 nt 0.3762
hsa_XPO1_0013100 Exon-Exon chr2:61719460-61729445 chr2:61492325-61502310 219 nt 0.3562
hsa_XPO1_0013200 Exon-Exon chr2:61719460-61749818 chr2:61492325-61522683 73 nt 0.3699
hsa_XPO1_0013300 Exon-Exon chr2:61719460-61761038 chr2:61492325-61533903 157 nt 0.3439
Showing 171 to 180 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].