Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0017000 Exon-Exon chr2:61722590-61749818 chr2:61495455-61522683 159 nt 0.3333
hsa_XPO1_0017100 Exon-Exon chr2:61722590-61764722 chr2:61495455-61537587 146 nt 0.3836
hsa_XPO1_0016500 Exon-Exon chr2:61722590-61764803 chr2:61495455-61537668 1160 nt 0.3853
hsa_chr2_0891600 Intergenic-Intergenic chr2:61722687-61764753 chr2:61495552-61537618 119 nt 0.4454
hsa_XPO1_0017700 Exon-Exon chr2:61724014-61725927 chr2:61496879-61498792 249 nt 0.3735
hsa_XPO1_0017800 Exon-Exon chr2:61724014-61749818 chr2:61496879-61522683 429 nt 0.3660
hsa_XPO1_0017900 Exon-Exon chr2:61724083-61726889 chr2:61496948-61499754 215 nt 0.3581
hsa_XPO1_0018000 Intron-Intron chr2:61724651-61724901 chr2:61497516-61497766 251 nt 0.3347
hsa_XPO1_0018200 Intron-Exon-Intron chr2:61725643-61726048 chr2:61498508-61498913 291 nt 0.3608
hsa_XPO1_0018100 Intron-Exon-Intron chr2:61725643-61727029 chr2:61498508-61499894 516 nt 0.3585
Showing 201 to 210 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].