Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0023700 Intron-Intron chr2:61744285-61745043 chr2:61517150-61517908 759 nt 0.4572
hsa_XPO1_0023800 Intron-Exon-Intron chr2:61744330-61761557 chr2:61517195-61534422 250 nt 0.3200
hsa_XPO1_0023900 Intron-Intron chr2:61747195-61747871 chr2:61520060-61520736 677 nt 0.3796
hsa_chr2_0892500 Intergenic-Intergenic chr2:61747207-61747456 chr2:61520072-61520321 250 nt 0.3080
hsa_XPO1_0024000 Intron-Exon chr2:61747315-61764803 chr2:61520180-61537668 119 nt 0.4118
hsa_XPO1_0024100 Intron-Exon-Intron chr2:61747526-61753656 chr2:61520391-61526521 239 nt 0.4184
hsa_XPO1_0024200 Intron-Exon-Intron chr2:61747526-61761038 chr2:61520391-61533903 392 nt 0.4362
hsa_XPO1_0024300 Intron-Exon-Intron chr2:61747526-61761813 chr2:61520391-61534678 85 nt 0.6118
hsa_XPO1_0024900 Intron-Exon-Intron chr2:61749746-61751607 chr2:61522611-61524472 140 nt 0.3286
hsa_XPO1_0025000 Intron-Exon-Intron chr2:61749746-61751757 chr2:61522611-61524622 73 nt 0.3699
Showing 261 to 270 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].