Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0025100 Exon-Exon chr2:61749746-61753651 chr2:61522611-61526516 1162 nt 0.3296
hsa_XPO1_0025200 Intron-Exon-Intron chr2:61749746-61756294 chr2:61522611-61529159 333 nt 0.4565
hsa_XPO1_0025300 Exon-Exon chr2:61749746-61761064 chr2:61522611-61533929 330 nt 0.3727
hsa_XPO1_0025400 Exon-Exon chr2:61749746-61761068 chr2:61522611-61533933 401 nt 0.4040
hsa_XPO1_0025500 Intron-Exon-Intron chr2:61749746-61761789 chr2:61522611-61534654 304 nt 0.3882
hsa_XPO1_0025600 Exon-Exon chr2:61749746-61764040 chr2:61522611-61536905 234 nt 0.3932
hsa_XPO1_0025700 Exon-Exon chr2:61749746-61764718 chr2:61522611-61537583 163 nt 0.3497
hsa_XPO1_0025800 Exon-Exon chr2:61749746-61764722 chr2:61522611-61537587 388 nt 0.3763
hsa_XPO1_0026000 Exon-Exon chr2:61749778-61753597 chr2:61522643-61526462 84 nt 0.2857
hsa_XPO1_0026100 Exon-Exon chr2:61749778-61753640 chr2:61522643-61526505 127 nt 0.3307
Showing 271 to 280 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].