Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0008000 Exon-Exon chr2:61715300-61717911 chr2:61488165-61490776 426 nt 0.3826
hsa_XPO1_0008100 Exon-Exon chr2:61715300-61720188 chr2:61488165-61493053 1068 nt 0.3708
hsa_XPO1_0008200 Exon-Exon chr2:61715300-61727029 chr2:61488165-61499894 1905 nt 0.3685
hsa_XPO1_0008300 Exon-Exon chr2:61715300-61729445 chr2:61488165-61502310 2012 nt 0.3673
hsa_XPO1_0008400 Exon-Exon chr2:61715300-61753656 chr2:61488165-61526521 2187 nt 0.3676
hsa_XPO1_0008500 Exon-Exon chr2:61715300-61761038 chr2:61488165-61533903 2319 nt 0.3700
hsa_XPO1_0009600 Exon-Exon chr2:61717777-61717911 chr2:61490642-61490776 135 nt 0.3926
hsa_XPO1_0009700 Exon-Exon chr2:61717777-61720188 chr2:61490642-61493053 777 nt 0.3681
hsa_XPO1_0009800 Exon-Exon chr2:61717777-61722748 chr2:61490642-61495613 1134 nt 0.3668
hsa_XPO1_0009900 Exon-Exon chr2:61717777-61724142 chr2:61490642-61497007 1263 nt 0.3690
Showing 41 to 50 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].