Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0017300 Exon-Exon chr2:61724014-61727029 chr2:61496879-61499894 480 nt 0.3667
hsa_XPO1_0017400 Exon-Exon chr2:61724014-61729445 chr2:61496879-61502310 587 nt 0.3629
hsa_XPO1_0017500 Exon-Exon chr2:61724014-61753656 chr2:61496879-61526521 762 nt 0.3648
hsa_XPO1_0017600 Exon-Exon chr2:61724014-61761038 chr2:61496879-61533903 894 nt 0.3714
hsa_XPO1_0018400 Exon-Exon chr2:61725808-61726048 chr2:61498673-61498913 169 nt 0.3550
hsa_XPO1_0018500 Exon-Exon chr2:61725808-61727029 chr2:61498673-61499894 351 nt 0.3590
hsa_XPO1_0018600 Exon-Exon chr2:61725808-61729445 chr2:61498673-61502310 458 nt 0.3559
hsa_XPO1_0018700 Exon-Exon chr2:61725808-61753656 chr2:61498673-61526521 633 nt 0.3602
hsa_XPO1_0018800 Exon-Exon chr2:61725808-61761038 chr2:61498673-61533903 765 nt 0.3686
hsa_XPO1_0019400 Exon-Exon chr2:61726000-61749818 chr2:61498865-61522683 411 nt 0.3577
Showing 81 to 90 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].