Basic Information

Symbol
circZCCHC11
RNA Class
circRNA
Alias
Terminal Uridylyl Transferase 4 KIAA0191 ZCCHC11 TENT3A PAPD3 Zinc Finger CCHC Domain-Containing Protein 11 Zinc Finger CCHC-Type Containing 11 Terminal Uridylyltransferase 4 TUTase 4 Zinc Finger, CCHC Domain Containing 11 PAP Associated Domain Containing 3 EC 2.7.7.52 TUTase4
Location (GRCh37)
1:52959283-52975384 UCSC Genome Browser
Location (GRCh38)
Host gene
ZCCHC11
Host category
mRNA
Forensic tag(s)
Cause of death analysis Sudden cardiac death diagnosis
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_ZCCHC11_0022800 Exon-Exon chr1:52959283-52975384 chr1:52493611-52509712 436 nt 0.3670
Forensic Context

A study in humans demonstrated that circZCCHC11 is significantly increased in the serum exosomes of patients with metastatic pancreatic cancer, where its levels correlate with TNM stages and poor prognosis [Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery segments from a single autopsy case demonstrated that the circZCCHC11 was differentially expressed in both left anterior descending and right coronary artery samples, and its expression was validated by qRT-PCR [Hou et al. DOI:10.1002/jcla.23552].