Basic Information
Symbol
circZZZ3
RNA Class
circRNA
Alias
Zinc Finger ZZ-Type Containing 3
ATAC1
ZZ-Type Zinc Finger-Containing Protein 3
DKFZP564I052
ATAC Component 1 Homolog (Drosophila)
Zinc Finger, ZZ Domain Containing 3
ATAC Component 1 Homolog
Location (GRCh37)
1:78028446-78143986
UCSC Genome Browser
Location (GRCh38)
1:77562761-77678301
Host gene
ZZZ3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Other applications
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_ZZZ3_0012800 | Intron-Intron | chr1:78126982-78127660 | chr1:77661297-77661975 | 679 nt | 0.4212 |
| hsa_ZZZ3_0012900 | Intron-Intron | chr1:78128123-78128522 | chr1:77662438-77662837 | 400 nt | 0.4300 |
| hsa_ZZZ3_0013000 | Intron-Intron | chr1:78128123-78128536 | chr1:77662438-77662851 | 414 nt | 0.4324 |
| hsa_ZZZ3_0013100 | Intron-Intron | chr1:78131515-78133706 | chr1:77665830-77668021 | 2192 nt | 0.3910 |
| hsa_ZZZ3_0013200 | Intron-Intron | chr1:78135374-78139088 | chr1:77669689-77673403 | 250 nt | 0.4520 |
| hsa_chr1_1061900 | Intergenic-Intergenic | chr1:78136250-78140405 | chr1:77670565-77674720 | 250 nt | 0.3240 |
| hsa_ZZZ3_0013300 | Intron-Intron | chr1:78142574-78143802 | chr1:77676889-77678117 | 1229 nt | 0.3483 |
| hsa_chr1_1062000 | Intergenic-Intergenic | chr1:78143684-78143986 | chr1:77677999-77678301 | 303 nt | 0.3234 |
Showing 131 to 138 of 138 entries
Forensic Context
A study in human traumatic brain injury (TBI) patients identified the circZZZ3 as a top down-regulated circular RNA (fold change 0.39) in brain injury tissues compared to adjacent contusion tissues, with its decreased expression validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553]. Circular RNAs exhibit tissue-specific expression and function as miRNA sponges, transcriptional regulators, and molecular scaffolds, with specific circRNAs serving as biomarkers for neurological conditions [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].