Basic Information
Symbol
circZZZ3
RNA Class
circRNA
Alias
Zinc Finger ZZ-Type Containing 3
ATAC1
ZZ-Type Zinc Finger-Containing Protein 3
DKFZP564I052
ATAC Component 1 Homolog (Drosophila)
Zinc Finger, ZZ Domain Containing 3
ATAC Component 1 Homolog
Location (GRCh37)
1:78028446-78143986
UCSC Genome Browser
Location (GRCh38)
1:77562761-77678301
Host gene
ZZZ3
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
Other applications
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_ZZZ3_0004900 | Exon-Exon | chr1:78046683-78107340 | chr1:77580998-77641655 | 2382 nt | 0.4064 |
| hsa_ZZZ3_0006000 | Exon-Exon | chr1:78047664-78105287 | chr1:77581979-77639602 | 1997 nt | 0.4096 |
| hsa_ZZZ3_0006300 | Intron-Exon-Intron | chr1:78063380-78099090 | chr1:77597695-77633405 | 250 nt | 0.3600 |
| hsa_ZZZ3_0007400 | Intron-Exon-Intron | chr1:78087377-78107340 | chr1:77621692-77641655 | 250 nt | 0.3480 |
| hsa_ZZZ3_0008200 | Intron-Exon-Intron | chr1:78097520-78107340 | chr1:77631835-77641655 | 1922 nt | 0.4032 |
| hsa_ZZZ3_0008900 | Exon-Exon | chr1:78097535-78099090 | chr1:77631850-77633405 | 1556 nt | 0.4139 |
| hsa_ZZZ3_0009000 | Exon-Exon | chr1:78097535-78107340 | chr1:77631850-77641655 | 1907 nt | 0.4043 |
| hsa_ZZZ3_0010000 | Exon-Exon | chr1:78098800-78107340 | chr1:77633115-77641655 | 642 nt | 0.3910 |
| hsa_ZZZ3_0011600 | Exon-Exon | chr1:78105134-78107340 | chr1:77639449-77641655 | 351 nt | 0.3618 |
| hsa_ZZZ3_0011900 | Intron-Exon-Intron | chr1:78105134-78141374 | chr1:77639449-77675689 | 250 nt | 0.2520 |
Showing 11 to 20 of 138 entries
Forensic Context
A study in human traumatic brain injury (TBI) patients identified the circZZZ3 as a top down-regulated circular RNA (fold change 0.39) in brain injury tissues compared to adjacent contusion tissues, with its decreased expression validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553]. Circular RNAs exhibit tissue-specific expression and function as miRNA sponges, transcriptional regulators, and molecular scaffolds, with specific circRNAs serving as biomarkers for neurological conditions [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].