Cytoplasmic Polyadenylation Element Binding Protein 1
CPEB
Cytoplasmic Polyadenylation Element-Binding Protein 1
CPE-Binding Protein 1
FLJ13203
CPE-BP1
HCPEB-1
H-CPEB
CPEB-1
This gene encodes a member of the cytoplasmic polyadenylation element binding protein family. This highly conserved protein binds to a specific RNA sequence, called the cytoplasmic polyadenylation element, found in the 3' untranslated region of some mRNAs. The encoded protein functions in both the cytoplasm and the nucleus. It is involved in the regulation of mRNA translation, as well as processing of the 3' untranslated region, and may play a role in cell proliferation and tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Forensic Context
A study in mice demonstrated that the protein Cpeb3, a potential target of the CPEB1, is involved in methamphetamine-induced behavioral sensitization within the nucleus accumbens [Li et al. DOI:10.1111/adb.12881].