Basic Information

Symbol
CRIP1
RNA class
mRNA
Alias
Cysteine Rich Protein 1 CRIP Cysteine-Rich Protein 1 (Intestinal) Cysteine-Rich Intestinal Protein Cysteine-Rich Heart Protein Cysteine-Rich Protein 1 CRP-1 CRHP CRP1 HCRHP
Location (GRCh38)
14:105484603-105488947
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Chronological age estimation
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001311.5
Sequence length
672.0 nt
GC content
0.6354

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-288.00 kcal/mol
Thermodynamic ensemble
Free energy: -299.63 kcal/mol
Frequency: 0.0000
Diversity: 181.88
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
...(((((..(((...((((((.(((....))...((((.(((..(((((((((((((.............))))))))))).))..))).))))(((((((((.((((.((((((((((.(((((.(((((.(((((.((.((......))))..).)))).....(((((((((.((((.....))))((((((....)))))).((((((((.(((((((..(((.(((((...((((..(...(((((.....(.(........).)..))))).)..))))..))))).........(((.....((((((...(((((((.(..((((......((((((.(((........))).)))))).((((.((..........)).)))).....))))..).)))))))..))))))....)))...)))..))))))).))))))))...((.(((...))))))))))))))...........((((.....))))((((..((....)).)))))))))...))).))))).))))))).).))..).)).)))))))).)))))).((((((((((..((((...))))...))....))))))))....((((((((...((((((.......))))))...)).)))))))))..).)))).
Thermodynamic Ensemble Prediction
...{((((..(({...((((((,{{{....,,.,.((((.(((..{((((((((((((.............))))))))))),}}..})),))))(((((((((.{(((.(((((((((({({{((.(((((.((((,,((.((......))||,.|.|}}}...{.(((((((((.((((.....))))((((((....)))))).((((((((.(((((((..(((.(((((...((((.,{...(((((...,.{.{.....,},},}..))))),}..))))..))))).........{{,.....((((((.,.(((((((.{..((((,{....((((((.(((........))).)))))).{{{{.,,..,,...{{,||.)}}},....))))..).))))))),,))))))....,}}...)))..))))))).)))))))),..{{.(((...)))}}))))))))),,,,.......((((.....))))((((..({....)}.)))))))}}...)))}).))).))))))).).))..}.)).))))))),.)))))).((((((((((.,((({...)))),,,))....})))))))....(((((({(...((((((.......))))))...)).))))))}))..).)))),

Transcripts

ID Sequence Length GC content
NM_001311.5 NCBI
CUUUUGCCUCGGAACUGGACCCGGGAGACAUCACAGCGCUGGGCUAGGG… 672 nt 0.6354
Summary

Cysteine-rich intestinal protein (CRIP) belongs to the LIM/double zinc finger protein family, members of which include cysteine- and glycine-rich protein-1 (CSRP1; MIM 123876), rhombotin-1 (RBTN1; MIM 186921), rhombotin-2 (RBTN2; MIM 180385), and rhombotin-3 (RBTN3; MIM 180386). CRIP may be involved in intestinal zinc transport (Hempe and Cousins, 1991 [PubMed 1946385]).[supplied by OMIM, Mar 2008]

Forensic Context

A review of human studies summarizing multi-omics approaches for biological age estimation identified the CRIP1 as a transcriptomic feature positively associated with aging in whole blood samples from a cohort of healthy people [Solovev et al. DOI:10.1016/j.mad.2019.111192].