Basic Information

Symbol
DYNLRB2
RNA class
mRNA
Alias
Dynein Light Chain Roadblock-Type 2 DNLC2B ROBLD2 DNCL2B Dynein, Cytoplasmic, Light Polypeptide 2B Roadblock Domain-Containing Protein 2 Dynein Light Chain 2B, Cytoplasmic Testicular Tissue Protein Li 53 Roadblock Domain Containing 2 Bithoraxoid-Like Protein
Location (GRCh38)
16:80540734-80550811
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_130897.3
Sequence length
628.0 nt
GC content
0.4220

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-155.90 kcal/mol
Thermodynamic ensemble
Free energy: -170.15 kcal/mol
Frequency: 0.0000
Diversity: 137.66
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.........((((((((.....)))))))).((((.(((.((((((((..((((((....)))..).))..))))))))))).))))..((((((((((((..((((...)))).)))(((((.....(((((((((((((................(((((((((((((....(((((....(((((((..........)))))))..(((.(((.(((....((....))....))).)))....)))..)))))((((.((((((((.((((...........)))).))))))))))))............(((.(((.....))))))..)))))))))))))...((((((((.(.....).))))).))).((.((.(((((((..(((((...((((.....)))).)))))))))))).)).)).((((......))))........))))).)))))))).....)))))..))))))))).((((...((((...((((..((.((..(((((......)))))...)).))...))))...)))))))).....(((((((((((((......((...((((((...)))))).))...))).))))))).)))..
Thermodynamic Ensemble Prediction
{,.,,.{{{((((((((.....)))))))).((((.{{((((((((((..(({(((....)))..}.))..))))))))))}.))))..((((((((((((..((((...)))).)))(((((.....(((((((((((((...,,,{,{,,.,{{,(((((((((((((.,{{{(({{....{((({{{..........)))))},..,{{.(((.(((.,..((....))....))).)))....}}}..}|||,((((.((((((((.((((.,.........)))).))))))))))))..},..|,||..,{|,||{.....}}})))..)))))))))))))...((((((((.{.....).))))).))).{(.((.(((((((..{{(((,{.(,,,....,}))},)}}}}))))))).)).}}.|{|{......,}}),},,,,,.))))).)))))))).....)))))..))))))))).,.,,...{{{{...{{{{..{{,((,.(((((......)))))...,),)).|.}}})...)))})),)}....(((((((((((((.,....(,...{{{{|,...)))}}}.,,...))),})))))).)))..

Transcripts

ID Sequence Length GC content
NM_001305017.2 NCBI
GUGGUUAUCACAUUAAUUCGUGCCUCAAUGAAUGAAUGAAUGGACAAAC… 662 nt 0.4109
NM_130897.3 NCBI
GUCUCCUAGCAACGGCGGGUAGCGUUGUUGACAUCCCGGGAGGCUGUGC… 628 nt 0.4220
Summary

Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based movement. Predicted to be located in ciliary tip. Predicted to be part of cytoplasmic dynein complex. Predicted to be active in centrosome and cytoplasm. Biomarker of hepatocellular carcinoma. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in newborn rats demonstrated that the DYNLRB2 is a highly expressed RNA marker used for the identification of ependymal cells in the brain following hypoxic-ischemic encephalopathy [Chen et al. DOI:10.1096/fj.202402891RR].