ELAV Like RNA Binding Protein 4
PNEM
HUD
ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 4 (Hu Antigen D)
ELAV Like Neuron-Specific RNA Binding Protein 4
Paraneoplastic Encephalomyelitis Antigen HuD
ELAV-Like Protein 4
Hu Antigen D
ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 4
Hu-Antigen D
HuD
Enables mRNA 3'-UTR AU-rich region binding activity; poly(A) binding activity; and pre-mRNA intronic pyrimidine-rich binding activity. Involved in 3'-UTR-mediated mRNA stabilization; RNA processing; and positive regulation of 3'-UTR-mediated mRNA stabilization. Predicted to be located in axon; cytoplasm; and dendrite. Predicted to be part of ribonucleoprotein complex. Predicted to be active in glutamatergic synapse. [provided by Alliance of Genome Resources, Jul 2025]
Forensic Context
A study in rats demonstrated that the ELAVL4, a neuronal-specific RNA binding protein, was part of a cluster of genes whose expression was inversely correlated with injury severity following experimental contusive spinal cord injury [De Biase et al. DOI:10.1152/physiolgenomics.00081.2005].