Basic Information
Symbol
APOD
RNA class
mRNA
Alias
Apolipoprotein D
Apo-D
ApoD
Location (GRCh38)
3:195568705-195584033
Forensic tag(s)
Wound age identification
MANE select
Transcript ID
NM_001647.4
Sequence length
862.0 nt
GC content
0.4872
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-220.84 kcal/mol
Thermodynamic ensemble
Free energy:
-237.30 kcal/mol
Frequency:
0.0000
Diversity:
182.58
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
..((..(((((........(((((.......(((((((.....(.((((...)))).)......)))))))........))))).......((((((((((.((((((..(.((.((((....((((((((.........)))))))))))).)).)..))))))))))))))))..)))))......((((......))))((..((.(((((((.((((.....(((.(((((((((...((..((((...........))))..))..(((...(((((...(((......((((....(((....(((...((((..((((.(((((((((((.....((((...((..((((((.......(...((((....))))...)......))))))..)).....))))............)))))))))))((((...))))...)))).)))))))....)))....))))......)))...))))).)))))))))...))).))).)))).))))))).))..))((((((.....((((....(((..........((((.......))))..............((.((((.((..........)).)))).)).......((((...)))).)))....))))))))))....(((...((((...(((((((((..(((.......((((((...((.(((((.((((..........................................))))))))).))....))))))......)))))).)))))).)))))))((((.((((.......)))).))))..(((((((....)))))))..))...
Thermodynamic Ensemble Prediction
..{,..(((((,,......(((((.....{.(((((((..,,.,,(((,...})}},)...,}.)))))))........))))).......((((((((((.((((((..(.((.((((...{((((((((..,....,.}))))))))))).)).,,.))))))))))))))))..})))}......((((......)))){|..((.(((((((.((((.....(((.(((((((({...,{{.{,...,,.|,,....,,}}|.{{,(({{{{.,({{{{||{{{{{.,,.((((((..(((..{(((............}))}...)))..)),,)))||{||..((..((((((....,,,,...((((....))))...),,....))))))..))..,,,,}}}||,,,...{{{{|||,{{{{{...((({..||,.((,...,))..))))))....}}}}|,}}}}}}}.,}}.,,))),}}})).})))))..,))).))).)))).))))))).))..}}((((((.....((({.,..{((..........((({.......))))..............{(.((((.((..........)).)))).)}.......((((...)))).)))....))))))))))....{{{...((((...(((((((((..(((.......((((((...((.(((((.((((.......................................,..))))))))).))....))))))......)))))).)))))).))))}}}{(((.((((.......)))).))))..(((((((....)))))))..,},..
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| AAGACAGGCAUCUCAAAUCGGCUGAUUCUGCAUCUGGAAACUGCCUUCA… | 862 nt | 0.4872 |
Summary
This gene encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism. [provided by RefSeq, Aug 2008]
Forensic Context
A study in human skin wound healing identified the APOD as a marker for an APOD+ pro-inflammatory fibroblast subcluster (FB-II) [Liu et al. DOI:10.1016/j.stem.2024.11.013].