The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Forensic Context
A study in human body fluids demonstrated that the SLC22A6 is a urine-specific mRNA/circRNA biomarker, with its circular transcript form expressed at a low level [Liu et al. DOI:10.1007/s00414-019-02027-y]. This biomarker is recognized as a circular RNA marker for the forensic identification of urine [Courts et al. DOI:10.3238/arztebl.m2024.0051].