Basic Information
Symbol
BEX3
RNA class
mRNA
Alias
Brain Expressed X-Linked 3
DXS6984E
NADE
NGFRAP1
Hero20
HGR74
Bex
Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1
Ovarian Granulosa Cell 13.0 KDa Protein HGR74
P75NTR-Associated Cell Death Executor
Brain-Expressed X-Linked Protein 3
Protein BEX3
Nerve Growth Factor Receptor-Associated Protein 1
Location (GRCh38)
X:103376299-103378301
Forensic tag(s)
Other applications
MANE select
Transcript ID
NM_206917.3
Sequence length
810.0 nt
GC content
0.4617
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-239.30 kcal/mol
Thermodynamic ensemble
Free energy:
-254.89 kcal/mol
Frequency:
0.0000
Diversity:
226.77
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((..(((((.((((((((((.(((..((.....)).))).))))))).....((((((..(((((..((.(((((((.(((((.((....((((((((((....(((.(((((.....(((.........)))..((((((((....(((((..............))).))..))).)))))..............((.(((...))).)).((((.....)))).))).)))))...))).))))))))).))))).))))))).))...)))))..))))))........))).)))))...((((((((((((((.(((((((........((..(((((...((((((..((((.(((....(((((((((.(((((((((.(...((((((............))))))....).)))))))))(((((.((.....(((((((((((...((.................)).))))))))))).....))...))))).......))))))))))))))))..)))))).))))).))........))))))).).....)))).......((((((((...(((((((((((..(((((.(((((((.....))))......(((((((...)))))))...))).)))))..))....)))))))))))))))))..(((((((((.....)))..))))))....................)))))))))...(((((....)))))....(((((.............)))))...............)))).....
Thermodynamic Ensemble Prediction
.{{({((((((({{.((.((((((({{{{({....,,..}}}(((((({...,)))))))))),..|)}))))),{{{({(((((((....,)}))},)})),,,.}}((((((((((.{((.(((((...((((((.((((((((,{{{{{{(,,,,,,,...,.,.}}|.{{,||||||.,....,||{((((,,,,{.,{|},,{((.((({{{(.(((((.....((({{..((((((....((((.((((.,,...},))))))))..})))))..}))))....,,,.,,((((((((({(((((((..,.(((({...,.,..,{,{(({{,..},,}})}},..,...,({,......)),.........{(((((((((.(...((((((..,,....},..))))))....).)))))))))}})))).,..))))))),,}}}..))))))}.,,))))).)))))).))),,.{{{||.,|,,.....}}))}}},,..}),)))))))))})))))))).))))))......))))}.,.))),,.)))))))))}.......|,..((((((((,..(((((((((((..(((((.(((((((.....))))......{((((((...)))))))...))).)))))..))....)))))))))))))))))..,{{{{,(((.....)))..})))},.,,,....(((((((((.{{{......})})))))))))....,,,....|||||.............}}})).,.......,,.,..}}))},...
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| ACCGAGAAGAGUGACAGGGCUGUGCGCUCUGGGGCACCUCAUGCAGACG… | 993 nt | 0.4844 | |
| CUAAGUGUCUCCGCGGCGCACCUCGCGGCGAGAAUCCGGAGGAGAAGGA… | 1127 nt | 0.4623 | |
| ACUCGCGUCUGGCUACCAGCUCCCCGCUGCCCUGAGCUCGGCGGGCUGG… | 857 nt | 0.4527 | |
| ACUCGCGUCUGGCUACCAGCUCCCCGCUGCCCUGAGCUCGGCGGGCUGG… | 810 nt | 0.4617 |
Summary
Enables identical protein binding activity. Predicted to be involved in negative regulation of protein ubiquitination and signal transduction. Predicted to act upstream of or within extrinsic apoptotic signaling pathway via death domain receptors. Located in cytosol. [provided by Alliance of Genome Resources, Jul 2025]
Forensic Context
A study in humans demonstrated that the BEX3 was significantly downregulated in circulating T cells during the injury stage compared to the recovery stage in patients following major trauma [Rau et al. DOI:10.2147/JIR.S375881].