| ID | Sequence | Length | GC content |
|---|---|---|---|
| GCCUCUGCGCGCGGGAAGAUGGCGGAACAGGCUACCAAGUCCGUGCUGU… | 580 nt | 0.4914 | |
| GCCUCUGCGCGCGGGAAGAUGGCGGAACAGGCUACCAAGUCCGUGCUGU… | 1474 nt | 0.4179 | |
| GCCUCUGCGCGCGGGAAGAUGGCGGAACAGGCUACCAAGUCCGUGCUGU… | 1474 nt | 0.4118 |
The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2008]
A review of forensic body fluid identification methods notes that acid phosphatase (SAP) serves as the most popular presumptive test for semen, as it catalyzes the hydrolysis of organic phosphates [Virkler & Lednev DOI:10.1016/j.forsciint.2009.02.013]. The method's application is complicated by the presence of vaginal acid phosphatase (VAP), which can cause false positives during analysis.