Calcium/Calmodulin Dependent Protein Kinase II Inhibitor 1
CaMKIINalpha
Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor 1
CaMKII Inhibitory Protein Alpha
CaMKIIN-Alpha
PRO1489
Predicted to enable calcium-dependent protein kinase inhibitor activity and protein kinase binding activity. Predicted to be involved in long-term memory and positive regulation of inflammatory response. Predicted to be located in neuronal cell body and synapse. Implicated in ovarian cancer; ovarian carcinoma; and prostate adenocarcinoma. Biomarker of hepatocellular carcinoma; oral squamous cell carcinoma; papillary thyroid carcinoma; and prostate cancer. [provided by Alliance of Genome Resources, Jul 2025]
Forensic Context
A study in mice demonstrated that the CAMK2N1 was downregulated in the neocortex and corpus callosum-external capsule at 7 days post-injury following controlled cortical impact, as part of transcriptional responses to traumatic brain injury [Kounelis-Wuillaume et al. DOI:10.1177/08977151251390528].