| ID | Sequence | Length | GC content |
|---|---|---|---|
| AUCAUUUCUGCUCUGCACUUGGCACCAAGGCUGUCACCCUGUUACCUCC… | 1441 nt | 0.5177 | |
| ACUCUGCAAGGACCCGAGCUAUUUAUCCCUAGGUCCUUUCCUCCUGCAC… | 1422 nt | 0.5162 |
This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. This protein also has antimicrobial activity, displaying an antibacterial effect on S. pneumoniae, S. aureus, Non-typeable H. influenzae, and P. aeruginosa. Finally, the protein is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. [provided by RefSeq, Jul 2020]
A study in mice demonstrated that the CCL24 is a macrophage-secreted chemokine specifically expressed after postnatal day 1 myocardial infarction and can promote cardiomyocyte proliferation [Li et al. DOI:10.3389/fcvm.2022.768834].