CUGBP Elav-Like Family Member 5
BRUNOL5
RNA-Binding Protein BRUNOL-5
CELF-5
Bruno (Drosophila) -Like 5, RNA Binding Protein
Bruno-Like 5, RNA Binding Protein (Drosophila)
CUGBP, Elav-Like Family Member 5
Bruno-Like 5 RNA Binding Protein
CUG-BP- And ETR-3-Like Factor 5
CUG-BP And ETR-3 Like Factor 5
Bruno-Like Protein 5
BRUNOL-5
This gene encodes a member of the the CELF/BRUNOL protein family, which contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing and translation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
Forensic Context
A study in mice demonstrated that the CELF5 was one of the most significantly upregulated genes with a linear trend across increasing doses of whole-body irradiation in lung tissue [Aryankalayil et al. DOI:10.1080/09553002.2023.2214205].