Predicted to enable calcium ion binding activity. Predicted to be involved in several processes, including cilium movement; outer dynein arm assembly; and regulation of flagellated sperm motility. Located in sperm flagellum. Implicated in primary ciliary dyskinesia. [provided by Alliance of Genome Resources, Jul 2025]
Forensic Context
A study in mice demonstrated that the CLXN was up-regulated following γ-ray exposure, as part of an investigation into radiation-induced gene expression changes in liver tissue using oligonucleotide microarray and real-time PCR validation [Roudkenar et al. DOI:10.1269/jrr.07078].