Basic Information

Symbol
circRAPGEF6
RNA Class
circRNA
Alias
Rap Guanine Nucleotide Exchange Factor 6 RA-GEF-2 PDZ-GEF2 PDZGEF2 PDZ Domain Containing Guanine Nucleotide Exchange Factor (GEF) 2 PDZ Domain-Containing Guanine Nucleotide Exchange Factor 2 Rap Guanine Nucleotide Exchange Factor (GEF) 6 PDZ Domain-Containing Guanine Nucleotide Exchange Factor I KIA001LB RAGEF2
Location (GRCh37)
5:130759766-130970853 UCSC Genome Browser
Location (GRCh38)
5:131424073-131635160
UCSC Genome Browser Search in Marker Scope
Host gene
RAPGEF6
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_RAPGEF6_0018300 Exon-Exon chr5:130840319-130846184 chr5:131504626-131510491 627 nt 0.4195
hsa_RAPGEF6_0018400 Exon-Exon chr5:130840319-130857214 chr5:131504626-131521521 759 nt 0.4256
hsa_RAPGEF6_0018500 Exon-Exon chr5:130840319-130883883 chr5:131504626-131548190 903 nt 0.4175
hsa_RAPGEF6_0019600 Intron-Exon chr5:130843760-130883879 chr5:131508067-131548186 591 nt 0.4315
hsa_RAPGEF6_0020400 Exon-Exon chr5:130857083-130883883 chr5:131521390-131548190 276 nt 0.4130
hsa_RAPGEF6_0020500 Exon-Exon chr5:130857083-130897740 chr5:131521390-131562047 346 nt 0.4046
hsa_RAPGEF6_0020600 Exon-Exon chr5:130857083-130928159 chr5:131521390-131592466 430 nt 0.4163
hsa_RAPGEF6_0020700 Exon-Exon chr5:130857083-130940386 chr5:131521390-131604693 558 nt 0.4014
hsa_RAPGEF6_0021300 Exon-Exon chr5:130883740-130897740 chr5:131548047-131562047 214 nt 0.3738
hsa_RAPGEF6_0021400 Intron-Exon-Intron chr5:130883740-130899640 chr5:131548047-131563947 2114 nt 0.3240
Showing 31 to 40 of 253 entries
Forensic Context

A study in mice demonstrated that the circRAPGEF6 was differentially expressed in methamphetamine-treated primary cortical neurons, with RNA sequencing indicating up-regulation, though qRT-PCR validation showed an opposite expression pattern [Li et al. DOI:10.1016/J.Neulet.2019.02.032].