Basic Information
Symbol
circRAPGEF6
RNA Class
circRNA
Alias
Rap Guanine Nucleotide Exchange Factor 6
RA-GEF-2
PDZ-GEF2
PDZGEF2
PDZ Domain Containing Guanine Nucleotide Exchange Factor (GEF) 2
PDZ Domain-Containing Guanine Nucleotide Exchange Factor 2
Rap Guanine Nucleotide Exchange Factor (GEF) 6
PDZ Domain-Containing Guanine Nucleotide Exchange Factor I
KIA001LB
RAGEF2
Location (GRCh37)
5:130759766-130970853
UCSC Genome Browser
Location (GRCh38)
5:131424073-131635160
Host gene
RAPGEF6
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_RAPGEF6_0000800 | Exon-Exon | chr5:130764595-130778230 | chr5:131428902-131442537 | 1359 nt | 0.4687 |
| hsa_RAPGEF6_0001500 | Exon-Exon | chr5:130766552-130767042 | chr5:131430859-131431349 | 491 nt | 0.4562 |
| hsa_RAPGEF6_0001600 | Exon-Exon | chr5:130766552-130769237 | chr5:131430859-131433544 | 606 nt | 0.4736 |
| hsa_RAPGEF6_0001700 | Exon-Exon | chr5:130766552-130769302 | chr5:131430859-131433609 | 671 nt | 0.4739 |
| hsa_RAPGEF6_0001800 | Exon-Exon | chr5:130766552-130775408 | chr5:131430859-131439715 | 855 nt | 0.4596 |
| hsa_RAPGEF6_0002000 | Exon-Exon | chr5:130766552-130778230 | chr5:131430859-131442537 | 324 nt | 0.4444 |
| hsa_RAPGEF6_0002100 | Exon-Exon | chr5:130766552-130782396 | chr5:131430859-131446703 | 221 nt | 0.4751 |
| hsa_RAPGEF6_0001900 | Exon-Exon | chr5:130766552-130788870 | chr5:131430859-131453177 | 1413 nt | 0.4607 |
| hsa_RAPGEF6_0001100 | Exon-Exon | chr5:130766552-130799974 | chr5:131430859-131464281 | 2250 nt | 0.4271 |
| hsa_RAPGEF6_0001200 | Exon-Exon | chr5:130766552-130808437 | chr5:131430859-131472744 | 2423 nt | 0.4309 |
Showing 51 to 60 of 253 entries
Forensic Context
A study in mice demonstrated that the circRAPGEF6 was differentially expressed in methamphetamine-treated primary cortical neurons, with RNA sequencing indicating up-regulation, though qRT-PCR validation showed an opposite expression pattern [Li et al. DOI:10.1016/J.Neulet.2019.02.032].