Basic Information
Symbol
circRAPGEF6
RNA Class
circRNA
Alias
Rap Guanine Nucleotide Exchange Factor 6
RA-GEF-2
PDZ-GEF2
PDZGEF2
PDZ Domain Containing Guanine Nucleotide Exchange Factor (GEF) 2
PDZ Domain-Containing Guanine Nucleotide Exchange Factor 2
Rap Guanine Nucleotide Exchange Factor (GEF) 6
PDZ Domain-Containing Guanine Nucleotide Exchange Factor I
KIA001LB
RAGEF2
Location (GRCh37)
5:130759766-130970853
UCSC Genome Browser
Location (GRCh38)
5:131424073-131635160
Host gene
RAPGEF6
Host category
mRNA
Forensic tag(s)
Drug abuse diagnoses
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_RAPGEF6_0003900 | Intron-Exon-Intron | chr5:130775274-130808512 | chr5:131439581-131472819 | 1778 nt | 0.4106 |
| hsa_RAPGEF6_0003300 | Exon-Exon | chr5:130775274-130828478 | chr5:131439581-131492785 | 2257 nt | 0.4081 |
| hsa_RAPGEF6_0003400 | Exon-Exon | chr5:130775274-130831353 | chr5:131439581-131495660 | 2365 nt | 0.4042 |
| hsa_RAPGEF6_0003500 | Exon-Exon | chr5:130775274-130846184 | chr5:131439581-131510491 | 250 nt | 0.3600 |
| hsa_RAPGEF6_0004700 | Exon-Exon | chr5:130775274-130857214 | chr5:131439581-131521521 | 132 nt | 0.4545 |
| hsa_RAPGEF6_0004800 | Exon-Exon | chr5:130775274-130883883 | chr5:131439581-131548190 | 150 nt | 0.3733 |
| hsa_RAPGEF6_0003600 | Intron-Exon-Intron | chr5:130775274-130884750 | chr5:131439581-131549057 | 250 nt | 0.4000 |
| hsa_RAPGEF6_0004900 | Intron-Exon-Intron | chr5:130775274-130884754 | chr5:131439581-131549061 | 123 nt | 0.5366 |
| hsa_RAPGEF6_0005000 | Exon-Exon | chr5:130775274-130928159 | chr5:131439581-131592466 | 154 nt | 0.4221 |
| hsa_RAPGEF6_0003700 | Exon-Exon | chr5:130775274-130940386 | chr5:131439581-131604693 | 250 nt | 0.3080 |
Showing 81 to 90 of 253 entries
Forensic Context
A study in mice demonstrated that the circRAPGEF6 was differentially expressed in methamphetamine-treated primary cortical neurons, with RNA sequencing indicating up-regulation, though qRT-PCR validation showed an opposite expression pattern [Li et al. DOI:10.1016/J.Neulet.2019.02.032].