Basic Information

Symbol
circSHPRH
RNA Class
circRNA
Alias
SNF2 Histone Linker PHD RING Helicase BA545I5.2 KIAA2023 SNF2, Histone-Linker, PHD And RING Finger Domain-Containing Helicase SNF2 Histone Linker PHD RING Helicase, E3 Ubiquitin Protein Ligase RING-Type E3 Ubiquitin Transferase SHPRH E3 Ubiquitin-Protein Ligase SHPRH FLJ90837 2610103K11Rik EC 2.3.2.27 EC 3.6.4.- RAD5
Location (GRCh37)
6:146106726-146285233 UCSC Genome Browser
Location (GRCh38)
6:145785590-145964097
UCSC Genome Browser Search in Marker Scope
Host gene
SHPRH
Host category
mRNA
Forensic tag(s)
Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SHPRH_0004600 Exon-Exon chr6:146209156-146256577 chr6:145888020-145935441 2398 nt 0.4358
hsa_SHPRH_0004700 Exon-Exon chr6:146209156-146261937 chr6:145888020-145940801 2477 nt 0.4380
hsa_SHPRH_0004800 Exon-Exon chr6:146209156-146276490 chr6:145888020-145955354 250 nt 0.3440
hsa_SHPRH_0006200 Exon-Exon chr6:146214351-146216113 chr6:145893215-145894977 359 nt 0.4345
hsa_SHPRH_0006300 Exon-Exon chr6:146214351-146273614 chr6:145893215-145952478 250 nt 0.3400
hsa_SHPRH_0006700 Exon-Exon chr6:146215286-146216113 chr6:145894150-145894977 180 nt 0.4056
hsa_SHPRH_0006800 Exon-Exon chr6:146215286-146234685 chr6:145894150-145913549 441 nt 0.4331
hsa_SHPRH_0007100 Exon-Exon chr6:146215286-146244921 chr6:145894150-145923785 1293 nt 0.4215
hsa_chr6_0217600 Intergenic-Intergenic chr6:146224385-146224566 chr6:145903249-145903430 182 nt 0.2692
hsa_SHPRH_0009100 Exon-Exon chr6:146240484-146254314 chr6:145919348-145933178 1162 nt 0.4363
Showing 11 to 20 of 154 entries
Forensic Context

A review of literature indicates that the circSHPRH is a tumor suppressor in brain cancer, specifically glioblastoma, where it is downregulated and its encoded SHPRH-146aa peptide inhibits glioma growth [Di Agostino et al. DOI:10.3389/fcell.2020.00389]. A review of human studies indicates that the circSHPRH is downregulated in colorectal cancer tissues and is associated with metastasis and survival, while its overexpression inhibits proliferation and cell cycle progression [Lee et al. DOI:10.1016/j.biopha.2018.12.052].