Basic Information

Symbol
circSNCA
RNA Class
circRNA
Alias
Synuclein Alpha NACP Alpha-Synuclein PARK1 PD1 Synuclein, Alpha (Non A4 Component Of Amyloid Precursor) PARK4 Parkinson Disease (Autosomal Dominant, Lewy Body) 4 Non A4 Component Of Amyloid Precursor Non-A4 Component Of Amyloid Precursor Non A-Beta Component Of AD Amyloid Non-A Beta Component Of AD Amyloid Synuclein Alpha-140 I+/--Synuclein Α-Synuclein
Location (GRCh37)
4:90645338-90758129 UCSC Genome Browser
Location (GRCh38)
4:89724187-89836978
UCSC Genome Browser Search in Marker Scope
Host gene
SNCA
Host category
mRNA
Forensic tag(s)
Forensic psychiatry evaluation
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_SNCA_0000300 Exon-Exon chr4:90645970-90646465 chr4:89724819-89725314 496 nt 0.3407
hsa_SNCA_0000500 Exon-Exon chr4:90647721-90756843 chr4:89726570-89835692 133 nt 0.4737
hsa_SNCA_0000600 Intron-Intron chr4:90648077-90648325 chr4:89726926-89727174 137 nt 0.3723
hsa_SNCA_0000800 Intron-Exon-Intron chr4:90650345-90652167 chr4:89729194-89731016 280 nt 0.4536
hsa_SNCA_0000900 Exon-Exon chr4:90650345-90743453 chr4:89729194-89822302 84 nt 0.4643
hsa_SNCA_0000700 Exon-Exon chr4:90650345-90756843 chr4:89729194-89835692 415 nt 0.5012
hsa_SNCA_0001000 Intron-Intron chr4:90658273-90662352 chr4:89737122-89741201 267 nt 0.3783
hsa_SNCA_0001100 Intron-Exon-Intron chr4:90658273-90756843 chr4:89737122-89835692 508 nt 0.4626
hsa_SNCA_0001200 Intron-Exon-Intron chr4:90658838-90756843 chr4:89737687-89835692 198 nt 0.4394
hsa_SNCA_0001300 Intron-Intron chr4:90670764-90670950 chr4:89749613-89749799 187 nt 0.3422
Showing 11 to 20 of 38 entries
Forensic Context

A study in human SH-SY5Y cells demonstrated that the circSNCA functions as a sponge for miR-7, thereby up-regulating SNCA mRNA expression, which results in reduced autophagy and increased apoptosis [Di Agostino et al. DOI:10.3389/fcell.2020.00389].