Basic Information
Symbol
circSNCA
RNA Class
circRNA
Alias
Synuclein Alpha
NACP
Alpha-Synuclein
PARK1
PD1
Synuclein, Alpha (Non A4 Component Of Amyloid Precursor)
PARK4
Parkinson Disease (Autosomal Dominant, Lewy Body) 4
Non A4 Component Of Amyloid Precursor
Non-A4 Component Of Amyloid Precursor
Non A-Beta Component Of AD Amyloid
Non-A Beta Component Of AD Amyloid
Synuclein Alpha-140
I+/--Synuclein
Α-Synuclein
Location (GRCh37)
4:90645338-90758129
UCSC Genome Browser
Location (GRCh38)
4:89724187-89836978
Host gene
SNCA
Host category
mRNA
Forensic tag(s)
Forensic psychiatry evaluation
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_chr4_0635500 | Intergenic-Intergenic | chr4:90722244-90723121 | chr4:89801093-89801970 | 878 nt | 0.3428 |
| hsa_SNCA_0002200 | Intron-Intron | chr4:90736684-90738334 | chr4:89815533-89817183 | 1651 nt | 0.3180 |
| hsa_SNCA_0002400 | Exon-Exon | chr4:90743397-90749335 | chr4:89822246-89828184 | 185 nt | 0.5514 |
| hsa_SNCA_0002500 | Exon-Exon | chr4:90743397-90756843 | chr4:89822246-89835692 | 331 nt | 0.5106 |
| hsa_SNCA_0002600 | Exon-Exon | chr4:90743397-90757940 | chr4:89822246-89836789 | 378 nt | 0.5238 |
| hsa_SNCA_0002700 | Exon-Exon | chr4:90743460-90757934 | chr4:89822309-89836783 | 122 nt | 0.5410 |
| hsa_SNCA_0002800 | Exon-Exon | chr4:90749294-90756736 | chr4:89828143-89835585 | 81 nt | 0.5062 |
| hsa_SNCA_0002900 | Exon-Exon | chr4:90749294-90758129 | chr4:89828143-89836978 | 188 nt | 0.4840 |
Showing 31 to 38 of 38 entries
Forensic Context
A study in human SH-SY5Y cells demonstrated that the circSNCA functions as a sponge for miR-7, thereby up-regulating SNCA mRNA expression, which results in reduced autophagy and increased apoptosis [Di Agostino et al. DOI:10.3389/fcell.2020.00389].