Basic Information
Symbol
circTPCN1
RNA Class
circRNA
Alias
Two Pore Segment Channel 1
TPC1
KIAA1169
Voltage-Dependent Calcium Channel Protein TPC1
Two Pore Calcium Channel Protein 1
Two Pore Channel Protein 1
FLJ20612
Two-Pore Channel 1, Homolog
Location (GRCh37)
12:113663049-113736389
UCSC Genome Browser
Location (GRCh38)
12:113225244-113298584
Host gene
TPCN1
Host category
mRNA
Forensic tag(s)
Mechanical injury analysis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_TPCN1_0007500 | Exon-Exon | chr12:113729414-113729763 | chr12:113291609-113291958 | 154 nt | 0.5325 |
| hsa_TPCN1_0007600 | Exon-Exon | chr12:113729414-113730878 | chr12:113291609-113293073 | 294 nt | 0.5612 |
| hsa_TPCN1_0000100 | Exon-Exon | chr12:113663049-113664769 | chr12:113225244-113226964 | 330 nt | 0.5424 |
| hsa_TPCN1_0000300 | Intron-Exon-Intron | chr12:113664533-113676633 | chr12:113226728-113238828 | 250 nt | 0.3680 |
| hsa_TPCN1_0000500 | Exon-Exon | chr12:113664533-113707650 | chr12:113226728-113269845 | 220 nt | 0.6000 |
| hsa_TPCN1_0000600 | Exon-Exon | chr12:113664533-113711095 | chr12:113226728-113273290 | 237 nt | 0.5485 |
| hsa_TPCN1_0000400 | Exon-Exon | chr12:113664533-113722442 | chr12:113226728-113284637 | 1524 nt | 0.5564 |
| hsa_TPCN1_0000700 | Exon-Exon | chr12:113664536-113698297 | chr12:113226731-113260492 | 125 nt | 0.6080 |
| hsa_chr12_0099800 | Intergenic-Intergenic | chr12:113667586-113668418 | chr12:113229781-113230613 | 833 nt | 0.4694 |
| hsa_TPCN1_0000800 | Intron-Intron | chr12:113669460-113669972 | chr12:113231655-113232167 | 513 nt | 0.5185 |
Showing 31 to 40 of 90 entries
Forensic Context
A study in human traumatic brain injury (TBI) patients identified the circTPCN1 as a top up-regulated circular RNA (fold change 19.03) in brain injury tissues compared to adjacent contusion tissues, with its differential expression validated by qRT-PCR [Li et al. DOI:10.3389/fneur.2022.1086553]. The broader literature indicates that circular RNAs exhibit tissue-specific expression and can function as miRNA sponges, transcriptional regulators, and biomarkers for various conditions, including neurological disorders [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].