Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0002400 Exon-Exon chr2:61708320-61727029 chr2:61481185-61499894 103 nt 0.3495
hsa_XPO1_0002500 Exon-Exon chr2:61708320-61729445 chr2:61481185-61502310 159 nt 0.3648
hsa_XPO1_0002600 Exon-Exon chr2:61708320-61753656 chr2:61481185-61526521 97 nt 0.3505
hsa_XPO1_0001900 Exon-Exon chr2:61708320-61764803 chr2:61481185-61537668 250 nt 0.3720
hsa_XPO1_0003700 Exon-Exon chr2:61709515-61711240 chr2:61482380-61484105 175 nt 0.3829
hsa_XPO1_0003800 Exon-Exon chr2:61709515-61713097 chr2:61482380-61485962 295 nt 0.3525
hsa_XPO1_0003600 Exon-Exon chr2:61709515-61715406 chr2:61482380-61488271 766 nt 0.3708
hsa_XPO1_0003900 Exon-Exon chr2:61709515-61729175 chr2:61482380-61502040 45 nt 0.2889
hsa_XPO1_0003500 Exon-Exon chr2:61709515-61749818 chr2:61482380-61522683 2744 nt 0.3677
hsa_XPO1_0005600 Exon-Exon chr2:61710092-61711240 chr2:61482957-61484105 175 nt 0.3943
Showing 121 to 130 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].