Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0015400 Exon-Exon chr2:61721029-61724103 chr2:61493894-61496968 447 nt 0.3691
hsa_XPO1_0015500 Exon-Exon chr2:61721029-61725927 chr2:61493894-61498792 606 nt 0.3680
hsa_XPO1_0015600 Exon-Exon chr2:61721029-61753656 chr2:61493894-61526521 108 nt 0.3704
hsa_XPO1_0015300 Intron-Exon-Intron chr2:61721029-61761813 chr2:61493894-61534678 2026 nt 0.3731
hsa_XPO1_0015700 Exon-Exon chr2:61721029-61764803 chr2:61493894-61537668 198 nt 0.3889
hsa_chr2_0891500 Intergenic-Intergenic chr2:61721095-61724047 chr2:61493960-61496912 34 nt 0.3529
hsa_XPO1_0016600 Exon-Exon chr2:61722590-61724142 chr2:61495455-61497007 288 nt 0.3576
hsa_XPO1_0016700 Exon-Exon chr2:61722590-61725927 chr2:61495455-61498792 126 nt 0.3651
hsa_XPO1_0016800 Exon-Exon chr2:61722590-61729175 chr2:61495455-61502040 204 nt 0.3235
hsa_XPO1_0016900 Intron-Exon-Intron chr2:61722590-61747610 chr2:61495455-61520475 188 nt 0.4574
Showing 191 to 200 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].