Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0018300 Intron-Exon-Intron chr2:61725643-61761038 chr2:61498508-61533903 1922 nt 0.3439
hsa_XPO1_0018900 Exon-Exon chr2:61725808-61729175 chr2:61498673-61502040 231 nt 0.3506
hsa_XPO1_0019000 Exon-Exon chr2:61725808-61729410 chr2:61498673-61502275 94 nt 0.3723
hsa_XPO1_0019100 Exon-Exon chr2:61725808-61749818 chr2:61498673-61522683 126 nt 0.3492
hsa_XPO1_0019200 Exon-Exon chr2:61725808-61753651 chr2:61498673-61526516 169 nt 0.3550
hsa_XPO1_0019300 Exon-Exon chr2:61725808-61764803 chr2:61498673-61537668 515 nt 0.4097
hsa_XPO1_0019700 Exon-Exon chr2:61726000-61727029 chr2:61498865-61499894 235 nt 0.3617
hsa_XPO1_0019800 Exon-Exon chr2:61726000-61729175 chr2:61498865-61502040 94 nt 0.3191
hsa_XPO1_0019900 Exon-Exon chr2:61726000-61729445 chr2:61498865-61502310 342 nt 0.3567
hsa_XPO1_0020000 Exon-Exon chr2:61726000-61753656 chr2:61498865-61526521 1505 nt 0.3355
Showing 211 to 220 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].