Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0019500 Intron-Exon-Intron chr2:61726000-61756294 chr2:61498865-61529159 250 nt 0.3640
hsa_XPO1_0020100 Exon-Exon chr2:61726000-61761038 chr2:61498865-61533903 412 nt 0.3592
hsa_XPO1_0019600 Intron-Exon-Intron chr2:61726000-61761789 chr2:61498865-61534654 1396 nt 0.3732
hsa_XPO1_0020200 Exon-Exon chr2:61726000-61764803 chr2:61498865-61537668 90 nt 0.3222
hsa_XPO1_0020300 Intron-Intron chr2:61726065-61726847 chr2:61498930-61499712 783 nt 0.3602
hsa_XPO1_0020400 Exon-Exon chr2:61726848-61729175 chr2:61499713-61502040 227 nt 0.3480
hsa_XPO1_0020500 Exon-Exon chr2:61726848-61729445 chr2:61499713-61502310 289 nt 0.3564
hsa_XPO1_0020600 Exon-Exon chr2:61726848-61749818 chr2:61499713-61522683 180 nt 0.3556
hsa_XPO1_0020700 Exon-Exon chr2:61726848-61753656 chr2:61499713-61526521 466 nt 0.3841
hsa_XPO1_0020800 Exon-Exon chr2:61726848-61761038 chr2:61499713-61533903 548 nt 0.3796
Showing 221 to 230 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].