Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0022800 Intron-Intron chr2:61738982-61742176 chr2:61511847-61515041 250 nt 0.4280
hsa_chr2_0892200 Intergenic-Intergenic chr2:61740065-61742067 chr2:61512930-61514932 2003 nt 0.4518
hsa_XPO1_0022900 Intron-Intron chr2:61740162-61743620 chr2:61513027-61516485 250 nt 0.3760
hsa_XPO1_0023000 Intron-Intron chr2:61740278-61741700 chr2:61513143-61514565 1423 nt 0.4603
hsa_XPO1_0023100 Intron-Exon-Intron chr2:61741197-61753656 chr2:61514062-61526521 175 nt 0.3714
hsa_XPO1_0023200 Intron-Exon-Intron chr2:61741197-61761038 chr2:61514062-61533903 139 nt 0.5108
hsa_chr2_0892300 Intergenic-Intergenic chr2:61741664-61743644 chr2:61514529-61516509 1981 nt 0.4407
hsa_chr2_0892400 Intergenic-Intergenic chr2:61742573-61742764 chr2:61515438-61515629 192 nt 0.3802
hsa_XPO1_0023500 Intron-Exon-Intron chr2:61743477-61761038 chr2:61516342-61533903 240 nt 0.3917
hsa_XPO1_0023600 Intron-Intron chr2:61744127-61745724 chr2:61516992-61518589 1598 nt 0.4887
Showing 251 to 260 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].