Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0010000 Exon-Exon chr2:61717777-61726048 chr2:61490642-61498913 1432 nt 0.3673
hsa_XPO1_0010100 Exon-Exon chr2:61717777-61727029 chr2:61490642-61499894 1614 nt 0.3668
hsa_XPO1_0010200 Exon-Exon chr2:61717777-61729445 chr2:61490642-61502310 1721 nt 0.3655
hsa_XPO1_0010300 Intron-Exon-Intron chr2:61717777-61752468 chr2:61490642-61525333 250 nt 0.3480
hsa_XPO1_0010400 Exon-Exon chr2:61717777-61753656 chr2:61490642-61526521 1896 nt 0.3660
hsa_XPO1_0010500 Exon-Exon chr2:61717777-61761038 chr2:61490642-61533903 2028 nt 0.3688
hsa_XPO1_0011000 Exon-Exon chr2:61719170-61719333 chr2:61492035-61492198 164 nt 0.3902
hsa_XPO1_0011100 Exon-Exon chr2:61719170-61721226 chr2:61492035-61494091 840 nt 0.3690
hsa_XPO1_0011200 Exon-Exon chr2:61719170-61722748 chr2:61492035-61495613 999 nt 0.3634
hsa_XPO1_0011300 Exon-Exon chr2:61719170-61724142 chr2:61492035-61497007 1128 nt 0.3661
Showing 51 to 60 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].