Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0011400 Exon-Exon chr2:61719170-61727029 chr2:61492035-61499894 1479 nt 0.3644
hsa_XPO1_0011500 Exon-Exon chr2:61719170-61729445 chr2:61492035-61502310 1586 nt 0.3632
hsa_XPO1_0011600 Exon-Exon chr2:61719170-61761038 chr2:61492035-61533903 1893 nt 0.3671
hsa_XPO1_0013400 Exon-Exon chr2:61719702-61724142 chr2:61492567-61497007 807 nt 0.3656
hsa_XPO1_0013500 Intron-Exon-Intron chr2:61719702-61752468 chr2:61492567-61525333 250 nt 0.3400
hsa_XPO1_0013600 Exon-Exon chr2:61719702-61761038 chr2:61492567-61533903 1572 nt 0.3670
hsa_XPO1_0014700 Exon-Exon chr2:61721029-61722748 chr2:61493894-61495613 357 nt 0.3641
hsa_XPO1_0014800 Exon-Exon chr2:61721029-61724142 chr2:61493894-61497007 486 nt 0.3704
hsa_XPO1_0014900 Exon-Exon chr2:61721029-61726048 chr2:61493894-61498913 655 nt 0.3664
hsa_XPO1_0015000 Exon-Exon chr2:61721029-61727029 chr2:61493894-61499894 837 nt 0.3656
Showing 61 to 70 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].