Basic Information

Symbol
circXPO1
RNA Class
circRNA
Alias
Exportin 1 CRM1 CRM-1 Emb Chromosome Region Maintenance 1 Protein Homolog Exportin 1 (CRM1 Homolog, Yeast) Exportin-1 Exp1 Exportin-1 (Required For Chromosome Region Maintenance) Chromosome Region Maintenance 1 Homolog (Yeast) Chromosome Region Maintenance 1 Homolog Exportin 1 (CRM1, Yeast, Homolog)
Location (GRCh37)
2:61605498-61765418 UCSC Genome Browser
Location (GRCh38)
2:61378363-61538283
UCSC Genome Browser Search in Marker Scope
Host gene
XPO1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_XPO1_0015100 Exon-Exon chr2:61721029-61729445 chr2:61493894-61502310 944 nt 0.3633
hsa_XPO1_0015200 Exon-Exon chr2:61721029-61761038 chr2:61493894-61533903 1251 nt 0.3693
hsa_XPO1_0015800 Exon-Exon chr2:61722590-61722748 chr2:61495455-61495613 159 nt 0.3333
hsa_XPO1_0015900 Exon-Exon chr2:61722590-61726048 chr2:61495455-61498913 457 nt 0.3567
hsa_XPO1_0016000 Exon-Exon chr2:61722590-61727029 chr2:61495455-61499894 639 nt 0.3584
hsa_XPO1_0016100 Exon-Exon chr2:61722590-61729445 chr2:61495455-61502310 746 nt 0.3566
hsa_XPO1_0016200 Intron-Exon-Intron chr2:61722590-61752468 chr2:61495455-61525333 250 nt 0.3240
hsa_XPO1_0016300 Exon-Exon chr2:61722590-61753656 chr2:61495455-61526521 921 nt 0.3594
hsa_XPO1_0016400 Exon-Exon chr2:61722590-61761038 chr2:61495455-61533903 1053 nt 0.3656
hsa_XPO1_0017200 Exon-Exon chr2:61724014-61726048 chr2:61496879-61498913 298 nt 0.3691
Showing 71 to 80 of 290 entries
Forensic Context

A study in humans demonstrated that circXPO1 is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer, and its decreased expression in myocardial tissues is associated with improved cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in human coronary artery samples from a single autopsy case demonstrated that circXPO1 was identified as a co-overexpressed circRNA in both the left anterior descending and right coronary artery samples, classifying it as a potential biomarker associated with coronary atherosclerosis [Hou et al. DOI:10.1002/jcla.23552].